Origins: This 1995 article quite nicely sums up the issue of clomipramine, an anti-depressant drug, having the side effects of causing some of its users to experience orgasms when they yawn:
"There is a small subset of people who are affected this way," commented
One woman who took clomipramine told researchers it cured her depression but she wanted to go on taking it because of its peculiar properties. She found she could experience an orgasm even by deliberate yawning. And a man who had also taken the pills said he was "highly satisfied" with the drug's usefulness.
Around five per cent of clomipramine users report the side effect, though for most people the drug inhibits the ability to reach orgasm. The New Scientist says that the drug's users have been comparing notes on the Internet and speculating on its unusual consequences: people who experience it would presumably seek out the most boring person they could find at parties.
Last updated: 25 February 2006
The Daily Telegraph. "Sex Can Be a Big Yawn for Patients Who Take Anti-Depressant Drug." 4 September 1995 (p. 1).