http://www.snopes.com/medical/myths/visine.asp

Mickey Red Eyes

Claim:   A few drops of Visine brand eye drops taken internally will cause diarrhea.

Status:   False.

Example:   [Collected via e-mail, 2003]

I've heard that barmaids and cocktail waitresses have a secret for getting rid of obnoxious customers. Seems they use the eye medication Visine for a little Montezuma's revenge. A few eyedrops in someone's drink can apparently leave him sitting on the toilet for the rest of the evening with a nasty case of "the runs."

Origins:   The desire for revenge runs deep in all of us. Everyone who has ever been wronged has at one time or another felt the urge to strike a counterblow. Most of us don't indulge in this pursuit because we've deemed the cost of getting even too high to justify the benefits gained, yet we revel in thoughts of comeuppances doled out by others. Such imaginings give us the chance to vicariously experience the joys of retribution, joys we're not likely to sample in real life.

The "Visine slipped into the drink" pay back carries additional appeal because it seems to offer an effective yet harmless form of retaliation that could be easily and furtively administered even by the wimpiest of revenge seekers. Also, the mental image of an enemy sent hotfooting for the toilet is a hugely satisfying one, especially in a society that views fecal output as something to be ashamed of. An act of spite that forces the victim into making repeated visits to the john is regarded as not only extremely inconveniencing to him, but degrading as well.

Yet all is not well in revenge land. While it is true that Visine is readily obtainable (it's an non-prescription eye drop manufactured by pharmaceutical giant Pfizer), a drink spiked with it is not a sure-fire means of producing diarrhea in the one unfortunate enough to swallow it, and ingestion of such a concoction is downright dangerous, making this "harmless" form of retaliation fraught with hazard.

The active ingredient in Visine eye drops is Tetrahydrozoline HCl 0.05%. Swallowing this substance can result in a number of nasty effects, including: Pfizer's cautions to users of Visine include: "If swallowed, get medical help or contact a Poison Control Center right away." In view of the above list, that advice should not be taken lightly.

One thing tetrahydrozoline has not been known to do is to cause sudden onset bouts of severe diarrhea. Although this belief has been around for decades, and everyone knows someone who knows someone who really did administer a Visine mickey to a deserving miscreant and thereby caused him an immediate serious
case of the trots, there's no documented evidence the product would have that effect. Of the Visine poisoning cases studied by medical observers, we found none that mentioned diarrheal output brought about by the drug.

Yet if Visine doesn't cause diarrhea, it has done things far more terrible. Drinking it can (and has) caused severe depression of the central nervous system. In 1996, a two-year-old child who ingested at most 2 to 3 mL of Visine eye drops became dangerously lethargic and unresponsive to every stimulus except deep pain. Thanks to prompt medical attention the child recovered, but not before enduring intubation and two days' worth of mechanically-assisted breathing.

Medical literature reports other cases of small children brought to the brink of crisis by ingestion of tiny amounts of over-the-counter eye drops. The danger is real, and parents are well advised to keep eye drops away from children.

Yet it is not only toddlers who risk central nervous system shutdown or other dire results if they swallow Visine, as demonstrated by the following examples:
Revenge seekers still not quite convinced that a Visine mickey finn won't produce the diarrheal results they crave, or that the drinking of such a potion could potentially result in a life-threatening medical crisis in the object of their prank, should consider one final fact: the act of secreting noxious substances in ingestibles for the purpose of bringing harm to others is called poisoning. It matters not if actual harm results from the attempt — the act itself is enough to land one in the hoosegow.

Barbara "poison penned" Mikkelson

Sightings:   In an episode of television's CSI ("Revenge Is Best Served Cold," original air date 26 September 2002), a drink spiked in this fashion causes a death when the eye drops initiate a fatal reaction with chocolate the victim had eaten.

Additional information:
  Tetrahydrozoline Poisoning   Tetrahydrozoline Poisoning
  (National Institutes of Health)
Last updated:   8 March 2012

Urban Legends Reference Pages © 1995-2013 by Barbara and David P. Mikkelson.
This material may not be reproduced without permission.
snopes and the snopes.com logo are registered service marks of snopes.com.
 
  Sources Sources:
    Bongioanni, Carlos.   "Airman Sentenced to Life in Prison."
    Stars and Stripes.   22 May 2002.

    Flynn, George.   "Grocer Settles Suit Out of Court."
    The Houston Chronicle.   19 September 1997   (p. A30).

    Flynn, George.   "Customer Says Drink Spiked, Sues Health Food Store Here."
    The Houston Chronicle.   7 September 1997   (p. A32).

    Givens, Ann.   "Woman Ordered to Pay Poisoned Roommate's Hospital Bill."
    [New York] Newsday.   16 September 2008.

    Nunnally, Derrick.   "Visine Prank Leads to Day in Court."
    [Milwaukee] Journal Sentinel.   14 November 2006.

    Reza, H.G.   "Student Accused of Poison Attempt."
    Los Angeles Times.   10 October 2003   (Orange County Edition; p. B3).

    Tobias, Joseph.   "Central Nervous System Depression Following Accidental Ingestion of Visine Eye Drops."
    Clinical Pediatrics.   October 1996   (Vol. 35; pp. 539-540).

    Vanderhart, Dirk.   "Woman Accused of Trying to Kill Husband."
    Springfield News-Leader.   9 January 2009.

    Wolfhagen, F.H.J., et al.   "Severe Nausea and Vomiting with Timolol Eye Drops."
    The Lancet.   1 August 1998   (p. 373).

    North County Gazette.   "Woman Charged With Assault By Visine Eye Drops."
    19 June 2009.

    Stars and Stripes.   "Investigator Testifies That Airman Confessed to Eskew Killing."
    20 February 2002.

    WOIO-TV [Cleveland].   "Urban Legend Almost Kills Dad."
    16 February 2002.